Saturday, November 30, 2019

Third and Fourth World Countries Essay Example

Third and Fourth World Countries Paper It is true that malnutrition in children in Third and Fourth World countries have contributed to disease and death, but that is not the only factor affecting that area. Other areas of healthcare are also harming these countries.   Some of them involve malnutrition as well, while others involve poor sanitation.   It should be discussed that a look into a small subset of diseases is probably the best course in further assisting these poor nations. First, it is stated that if a child lives through childhood then the mothers in these nations will not have as many children.   This can be achieved by concentrating on a small grouping of diseases that are easily cured. We will write a custom essay sample on Third and Fourth World Countries specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Third and Fourth World Countries specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Third and Fourth World Countries specifically for you FOR ONLY $16.38 $13.9/page Hire Writer Many people concentrate too much on every single affliction instead of realizing a bigger picture forms in these nations.   As the WHO reported â€Å"the prospects of the poorest billion in the Third World can be radically improved by targeting a relatively small set of diseases and conditions.† (Fogel Lee, 2002)   Many of the cures are easy to administer and should be universal for all members of the human race. Nutrition and other needs are considered to be the big killers among these populations.   The facts on Third World and Fourth World needs are staggering. The Commission on Macroeconomics and Health (CMH) of the World Health Organization estimates â€Å"87 percent of deaths among children under age five, 71 percent of deaths between ages five and twenty-nine, and 47 percent of deaths between ages thirty and sixty-nine† can be eradicated by using existing drugs and vaccines, easily delivering food, and by public-health programs that promote positive sanitation and health. (Fogel Lee, 2002) The solutions to the problems seem easy to solve when a person thinks about the big diseases instead of every single problem facing Third and Fourth World countries. References Fogel, R. W., Lee, C. (2002). Who Gets Health Care?. Daedalus, 131(1), 107+.

Tuesday, November 26, 2019

Roman Aqueducts An Engineering Brilliance essays

Roman Aqueducts An Engineering Brilliance essays Roman Aqueducts: An Engineering Brilliance Transportation of water is a very important obstacle the world has taken on. Water is a necessity to live; therefore control of water in and out of towns has been going on for thousands of years. Many different ways of moving water from one spot to another have been tried over the years. One example is the building of dams, not only to generate electricity, but also to create an abundance of water that can be transported to farmers to water their crops. The water from the dam is sent through underground conduits, aqueducts, to its final destination. Aqueducts were used by Greeks, Assyrians, Babylonians, Persians and Egyptians for water transportation. These early civilizations provided the vision for the Roman Empire to perfect the use of the aqueduct. In 97 AD, Sextus Julius Frontinus, the city official in charge of the water supply, is recorded as saying: I ask you! Just compare this vast array of indispensable structures carrying so much water with the idle Pyramids or the world-famous but useless monuments of the Greeks." ( ) In 97 AD, 300 gallons of water per person a day flowed into Rome through nine aqueducts. The Romans had succeeded in their vision of an aqueduct system supplying Rome with water. Many people, including Frontinus, thought that the Roman aqueduct system was the greatest invention in the world because of what it brought to the people of Rome. In the early days of Rome, the water supply came from the River Tiber. The Tiber, however is a very muddy river, and Romes sewer system also contaminated it. By the 4th century the Roman population was growing rapidly and Rome urgently needed an alternate water supply. In 312 BC the Roman Senate ordered Adile Appius Claudius to find a new source of water for the city. Claudius undertook the mission and started construction of the first aqueduct into Rome (Carr). Aqua Appia was successfully comple...

Friday, November 22, 2019

Breakeven Point of Sales for Accounting

IN UNITS=   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  TOTAL FIXED COST  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  (Bazley, Hancock & Robinson, 2014).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  CONTRIBUTION PER UNIT IN DOLLARS=   Ã‚  Ã‚  TOTAL FIXED COST  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   (Cafferky, 2010).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  P/V RATIO Variable Manufacturing Cost Per Unit Proportionate Contribution Per Unit Weighted average contribution per unit P/V Ratio (Contribution Per Unit/Selling Price Per Unit)   Breakeven sales (units) = IN UNITS=  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   TOTAL FIXED COST   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  CONTRIBUTION PER UNIT     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = $270,000   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   $10.15  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = 26601 units   Now 26601 units have been divided in the proportion of 1:1:3 (as determined above) between the products viz. Squid, Proud Stash and Private zoo. Squid  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   =26601  Ã‚   x 1  Ã‚   = 5320 units Proud Stash = 26601  Ã‚   x 1 = 5320 units Private Zoo = 26601  Ã‚  Ã‚   x 3  Ã‚   =15961 units Breakeven sales (units) = IN DOLLARS=  Ã‚  Ã‚   TOTAL FIXED COST  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚        Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   P/V RATIO   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = $270,000   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   11.01%   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = $ 2452202 (difference in the sales amount because of rounding off the percentage of P/V ratio to 11.01%) Now sales of $245220 has been divided into the proportion of 1:1:3 (as determined above) between the products viz. Squid, Proud Stash and Private zoo. Squid  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = $2452202  Ã‚   x 1  Ã‚   = $490440 Proud Stash = $2452202  Ã‚   x 1  Ã‚   = $490440   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   5 Private Zoo = $2452202  Ã‚   x 3  Ã‚   = $1471321   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   5 Weighted average p/v ratio=  Ã‚   (18.75%x 0.2*)  Ã‚   +  Ã‚   (14.10%x 0.2)  Ã‚   +  Ã‚  Ã‚   (7.40%x 0.6 # )   =11.01% (The percentage figure has been rounded off and due to this reason there could be slight variation in the amount of breakeven sales figure.)#0.2 = 1/5 Weighted average contribution per unit= (12x 0.2)  Ã‚  Ã‚  Ã‚   +  Ã‚  Ã‚   (11x 0.2)  Ã‚  Ã‚  Ã‚   +  Ã‚  Ã‚  Ã‚   (9.25x 0.6)   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   = $10.15 Cafferky, M., 2010.  Breakeven Analysis: The definitive guide to cost-volume-profit analysis. Business Expert Press.

Wednesday, November 20, 2019

Toyota Motor Corporation Essay Example | Topics and Well Written Essays - 1500 words

Toyota Motor Corporation - Essay Example On pursuing its business model, Toyota periodically reviews the carrying value of its long-term assets used in the business, including intangible assets as circumstances deserve such review. The company carries out the review using estimates of future cash flows and fair value that the management think would influence the accurate valuation of assets. In the same way, Toyota also needs to consider the assets like high quality fixed income bonds and fixed income bonds that are presently available and anticipated to be available in the future. The company also takes into account the deferred tax assets as there are chances for the actual taxable income to differ from the estimated amounts due to various assumptions (Toyota Motor Corporation, 2010). There are liquid assets in the business which the company defines cash and cash equivalents, time deposits, marketable debt securities that are taken into account to make sure that the company is in line with its business model. However, goo dwill is not material to Toyota’s consolidated balance sheet, and intangible assets with a definite life are amortised on a straight-line basis with estimated useful lifetime of five year. Intangible assets with indefinite life are examined for impairment whenever incidents or circumstance signify that a carrying amount of an asset may not be recuperated. The company evaluates the impairment loss when carrying amount of an asset exceeds the estimated undiscounted cash flows. Toyota’s strategy and aim for plan asset management is to maximise returns on plan assets to meet future benefit payment requirements under risks that the company thinks to be permissible (Toyota Motor Corporation, 2010). Assets in financial accounting can be considered as the economic resources of the firm. Anything that is touchable or intangible and able to be owned by or administered to produce value by preserving it on the process of obtaining a positive economic value can be regarded as an as set. In simple worlds, asset can be stated as an ownership that can be converted into cash (cash itself is an asset). Asset in simple sense is anything of value that a company owns, including cash and should be recorded on the balance sheet of the company. Even if the firm used credit to purchase an asset, the company still owns it. In such case, the original cost of the asset must be recorded on the asst side of the balance sheet as well as the amount that the company owes should be recorded on the liability side of the balance sheet. The three components that constitute a company’s balance sheet, which illustrate the business’s financial position at any point are assets, liabilities, and owners’ equity (U.S. Securities Exchange Commission, 2007). This association among these three components can be explained using the following equation: Assets = Liabilities + Owners’ Equity This equation sets the framework for keeping trace of money as it flows in and out of the business. Every penny in the business should be recorded into appropriate ledgers, every single transaction into the books using a double-entry system of debit and credit. In general accounting practice, assets are recorded on the top left side of the balance sheet. Assets may be classified in many ways and the principal distinction normally made for business purposes is between: Fixed assets and Current assets. There are other business

Tuesday, November 19, 2019

Veganism Essay Example | Topics and Well Written Essays - 500 words

Veganism - Essay Example People like puppies, so they keep them in their laps, but would often forget to put them in the shelter when it’s raining out there. People who keep donkeys to use them as a means to travel and transport luggage over the cartridges beat them with lashes to make them run faster. So many animals are treated this way including horses, donkeys, ponies, and camels. People keep the dog for their safety, but when some dog catches a disease, he is shot dead! All life long, dogs bark at the outsiders for the protection of their masters, and the masters kill them when the dogs become useless. These are all cases of direct and overt subjugation of animals’ rights. Humans have also caused great loss to animals through their environment-unfriendly activities. Thousands of species of animals have become extinct as a result of the ever-increasing global warming. Humans happen to be the fundamental cause of this rise in temperature that has spoiled the natural habitat of thousands of a nimals. An in-depth analysis of the kind of treatment humans have given to the animals suggests that humans have largely been unfair to the animals and have always suppressed them. Animals are as much part of nature as are humans and they are as much creation of God as are humans. In light of these facts, it is a moral obligation upon every human being to take care of the animals. I have decided to become a vegan. This would enable me to take objective measures to protect the animals and provide them with a healthy and safe environment to live in.

Saturday, November 16, 2019

The Effects of Global Financial Crisis in Nigeria Essay Example for Free

The Effects of Global Financial Crisis in Nigeria Essay The global financial crisis began in the United States of America and the United Kingdom when the global credit market came to a standstill in July 2007 (Avgouleas, 2008). The crisis, brewing for a while, really started to show its effects in the middle of 2008. Around the world stock markets have fallen, large financial institutions have collapsed or been bought out, and governments in even the wealthiest nations have had to come up with rescue packages to bail out their financial systems. It is a well known fact that the world is now a global village. As a result of this, the global economic meltdown is having a side effect on Nigerians to an extent that people’s standard of living has been seriously affected. The side effects on Nigerians include high cost of commodities, upsurge in social vices and unemployment. As a way of managing the situation, the government should cut down on the salaries of public office holders and reduce excessive spending in order to utilize the little resources available to provide the needed infrastructural facilities that will make life meaningful to the people, and focus attention on important projects. The concept of financial crisis The term financial crisis is applied broadly to a variety of situations in which some financial institutions or assets suddenly lose a large part of their value. In the 19th and early 20th centuries, many financial crises were associated with banking panics, and many recessions coincided with these panics. Other situations that are often called financial crises include stock market crashes and the bursting of other financial bubbles, currency crises, and sovereign defaults (Kindleberger and Aliber, 2005, Laeven and Valencia, 2008). Causes of the Crisis The reasons for this crisis are varied and complex, but largely it can be attributed to a number of factors in both the housing and credit markets, which developed over an extended period of time. Some of these include: the inability of homeowner to make their mortgage payments, poor judgement by the borrower and/or lender, speculation and overbuilding during the boom period, risky mortgage products, high personal and corporate debt levels, financial innovation that distributed and concealed default risks, central bank policies, and regulation (Stiglitz,2008). Africa and the Global Financial Crisis The direct impact of the financial crisis on the African economies has thus far been limited as most commercial banks in the region refrained from investing in the troubled assets from the US and other part of the world. This is why most commentators argue that Africa is so far insulated from the direct effects of the financial crisis. The current financial crisis affects Africa and other developing countries in two possible ways; First, there could be financial contagion and spillovers for stock markets in Africa. Stock markets in the region showed some volatility, driven by a sell-off by foreign investors. The Nigerian stock market for instance has been experiencing a continuous downward trend in prices of stocks for over two months now. The India stock market dropped by 8% in one day at the same time as stock markets in the USA and Brazil plunged. Stock markets across the world – developed and developing – have all dropped substantially since May 2008. Share prices have tumble between 12 and 19% in the USA, UK and Japan in just one week, while the MSCI emerging market index fell 23%. This includes stock markets in Brazil, South Africa, India and China (ODI, 2008). We need to better understand the nature of the financial linkages, how they occur (as they do appear to occur) and whether anything can be done to minimise contagion. Possible Policy responses The current macro-economic and social challenges posed by the global financial crisis require a much better understanding of appropriate policy responses. Some recommended policy responses which can be applied to the situation in Nigeria are enumerated as follows: †¢ There needs to be a better understanding of what can provide financial stability, how crossborder cooperation can help to provide the public good of international financial rules and systems, and what the most appropriate rules are with respect to development. There needs to be an understanding of whether and how Nigeria and other developing countries can minimise financial contagion; †¢ Nigeria and other developing countries will also need to manage the implications of the current economic slowdown – after a period of strong and continued growth in developing countries, which has promoted interest in structural factors of growth, international macro economic management will now move up the policy agenda. †¢ Nigeria and other developing countries need to understand the social outcomes and provide appropriate social protection schemes. †¢ Central Banks should regulate issue of foreign exchange to companies during this time of crisis to avoid creating a deep in foreign reserves. †¢ Non-bank financial sector such as Pension Funds should also be regulated. This is to protect pension funds from being invested in some of this complex instruments to enable them meet their liquidity obligation as at when due. †¢ African countries should strengthen domestic and regional markets and boost intra-African trade and it is also important to promote domestic tourism. †¢ There is a need for new stability of the global financial system in which the voice of every nation, every continent is heard and their concerns taken into account. Conclusion The global financial crisis is already causing a considerable slowdown in most developed countries. Governments around the word are trying to contain the crisis, but many suggest the worst is not yet over. Stock markets are down more than 40% from their recent highs. Investment banks have collapsed, rescue packages are drawn up involving more than a trillion US dollars, and interest rates have been cut around the world with US and Japan cutting theirs to all time low of 0. 25% and 0. 1% respectively (bbc. co. uk), in what looks like a coordinated response. With a recession already in place in most developed countries, Nigeria and other developing countries should try and come up with policies that will minimise the spread of this crisis to their economy.

Thursday, November 14, 2019

Structure and Function Essay -- Medical Research

First labelled an oncogene upon its discovery in 1979, p53 (or TP53 in humans), was correctly re-labelled a tumour suppressor a decade later following the discovery that the gene previously being studied was, ironically, a mutant. Now realised as the most common mutated gene, found in a staggering 50% of cancers, p53 is a keystone in the face of cancer. Its structure and functions continue to be delved into. Amino acids, genome stability, tumour suppression, iPS? Gene Structure 53 kilo-Daltons in size, 11 exons and 10 introns, p53 gene is located on chromosome 17. Using a clone isolated from a cDNA library of simian virus 40- transformed human fibroblasts, Mcbride et al. (1985), identified the location of p53 gene. Using karyotypic analysis and Southern analyses, they narrowed down the exact position of the p53 gene to the most distal band on the short arm of chromosome 17- the telomeric band 17p13. Structurally abundant in domains, p53 has three main functional domains and 393 amino acids in total. The first domain, the N-terminal (NH2 terminal) houses amino acids that are important in transactivation. In vivo, p53 requires amino acids F19, L22, and W23 found in the N-terminal for transcriptional activation (Lin et al., 1995). Present also, are the amino acid residues 22 and 23, although positive- regulators of transcriptional activity, are later to play a role in the negative-regulation of p53. In highlighting similarities between p53 protein-DNA interactions to other protein-DNA complexes, Cho et al. (1994), point out that p53 uses a loop packing at the NH2-terminal part of the alpha helix to make extra connections to the bases in the major groove of DNA. The C-terminal (carboxyl terminal) —61 important amino aci... ...anaka, S., 2009. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460, 1132-1135. Lee, S., Elenbaas, B., Levine, A.J, and Griffith, J., 1995. p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 81, 1013-1020. Levine, A.J., 1997. p53, the cellular gatekeeper for growth and division. Cell. 88, 323-331. Lin, J., Wu, X., Chen, J., Chang, A., and Levine, A.J., 1995. Functions of the the p53 protein growth regulation and tumour suppression. Cold Springs Harbour Symposia on Quantitative Biology LIX, 215-223. McBride, O.W., Merry, D.E., Oren, M., and Givol, D., 1985. The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13). Proc. Nat. Acad. Sci. 83, 130-134.

Monday, November 11, 2019

Prevention Of Orthopaedic Implant Infection Health And Social Care Essay

Abstraction:The American Academy of Orthopaedic Surgeons ( AAOS ) and the American Dental Association ( ADA ) , along with 10 other academic associations and societies late ( December 2012 ) published their common clinical pattern guideline â€Å" Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures. † This evidence-based guideline, detailed in 325 pages, has three recommendations and substitutes the old AAOS guideline. The new published clinical guideline is a protocol to forestall patients set abouting dental processs from orthopedic implant infection. The guideline is developed on the footing of a collaborative systematic reappraisal to supply practical advice for preparation clinicians, tooth doctors and any qualified doctors who need to see bar of orthopedic implant ( prosthetic device ) infection in their patients. This systematic reappraisal found no expressed grounds of cause-and-effect relationship between dental processs and periprosth etic articulation infection ( PJI ) . This short communicating wants to show a graphic sum-up of AAOS/ADA clinical pattern guideline as a clinical update and an academic execution to inform and help Persian competent clinicians and tooth doctors in the class of their intervention determinations, to enrich the value and quality of wellness attention based on the latest international footing. â€Å" Evidence Insufficient to Recommend Prophylactic Antibiotics for Dental Patients with Orthopaedic Implants. † was one of the nailing headlines of the dental updates in the winter 2013. [ 4-7 ] The American Academy of Orthopaedic Surgeons ( AAOS ) and the American Dental Association ( ADA ) , along with 10 other academic associations and societies late ( December 2012 ) published their common clinical pattern guideline â€Å" Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures. † This 325-page evidence-based guideline has three recommendations and substitutes the old AAOS guideline. The new clinical pattern guideline was established utilizing the published AAOS CPG ( Clinical Practice Guideline ) development procedure and besides sing the all criterions recommended for systematic reappraisals and clinical pattern guidelines. The full guideline presents a comprehensive systematic reappraisal of available grounds directing on the bar of orthopedic implant ( OI ) infection in patients having dental processs. [ 1 ] Jevsar ( Chairman of AAOS group ) and Abt ( on behalf of ADA group ) published and editorial to this guideline and described how the recommendations have been evidence-based. They believe that antibiotic prophylaxis recommendations, in the 2009 AAOS information statement, can merely be regarded as an educational assistance and non as an official guideline. [ 3 ]SYNOPSIS OF THE NEW GUIDELINEThe workgroup, ab initio developed three recommendations for antibiotic prophylaxis in dental patients with joint replacings. These recommendations shaped the basic foundation for systematic reappraisals of the literature sing the alveolar consonant processs and periprosthetic articulation infection ( PJI ) . The workgroup besides determined elaborate standards for quality assessment of the published informations and accordingly avoiding any prejudice. To avoid prejudice, the AAOS uses specific words for its recommendations and gives rationals for their use. Due to the restrictions in available gro unds, the three recommendations presented in the new guideline are classified as limited, inconclusive, and consensus with one recommendation for each class of grounds. Higher class recommendations are relatively rare within published CPGs. The work squad emphasized that they did non say this new guideline to be an impartial papers. All three recommendations should be integrated into the decision-making procedure to better patient attention. The guideline accentuates on the coaction between the doctors, tooth doctors and patients to be after a intervention based on the grounds, clinical findings and patient penchants. [ 1-3 ] The undermentioned guideline is a sum-up of the AAOS-ADA recommendations for bar of OI infection in patients having procedural dental interventions.Recommendation 1.â€Å" The practician might see stoping the pattern of routinely ordering contraceptive antibiotics for patients with hip and knee prosthetic articulation implants undergoing dental processs. † [ 1 ]Bing graded as Limited, this recommendation is based on limited grounds and depicts that dental processs are non related to OI infection.Moreover, it indicates that practicians should see altering their customary pattern of ordering contraceptive antibiotics for dental patients. [ 1,5-7 ] The phrase limited is unequivocal ; which means low degrees of grounds is present to back up the recommendation.Practitioners should be watchful to up-coming publications that hold grounds and their determinations should reflect their single judgement and the patient ‘s penchants. [ 1 ] Stronger groundss support this recommendation compared to other two recommendations: Clinical practicians believe in altering their longstanding tradition in the prescription of contraceptive antibiotics for dental patients. The groundss indicate that dental processs are non linked to the OI infections. The hazard of OI infections is non reduced by the pre-procedural antibiotic prophylaxis. Strong grounds indicates that pre-procedural antibiotic prophylaxis reduces the incidence of bacteriemia induced by station dental process. No grounds proves that bacteriemia increases the hazard of OI infections [ 1,3,5 ]Recommendation 2.â€Å" The work group was unable to urge for or against the usage of topical unwritten disinfectants in patients with prosthetic articulation implants or other orthopedic implants undergoing dental processs. † [ 1 ] This recommendation is graded as Inconclusive, sing the strength of the grounds. The guidelines implies that practicians should see a small restraint in their determination that whether to follow an inconclusive recommendation or non. The guideline emphasizes that patient penchant should hold a important influencing function and practicians should carefully wait for future publications that elucidate the bing grounds to find the balance between benefits and possible hazard. [ 1,2,4 ] Apparently, this recommendation refers to the application of unwritten topical disinfectants in the bar of OI infections in dental patients. It indicates that there is no direct grounds to corroborate that application of unwritten topical antiseptics ( before alveolar consonant processs ) would cut down bactermia and hence prevent OI infections. [ 5 ] The guideline points out the followerss as illustrations of topical antiseptics administered by tooth doctors: Chlorhexidine Gluconate unwritten rinse, povidone-iodine oral cavity rinse, H peroxide oral cavity rinse and mouthrinses with sodium-p-toluene ( chloramine-T ) . [ 1-3,5 ]Recommendation 3.â€Å" In the absence of dependable grounds associating hapless unwritten wellness to prosthetic joint infection, it is the sentiment of the work group that patients with prosthetic articulation implants or other orthopedic implants maintain appropriate unwritten hygiene. † [ 1 ]This recommendation was graded as Consensus, bespeaking th at adept sentiment supports the guideline recommendation albeit the fact that no available grounds can meet the inclusion standards. The guideline emphasized on the imperative function of patients ‘ penchant in determination devising and besides affirmed the flexibleness of practicians in make up one's minding whether to follow a recommendation rated as Consensus or non. Consensus recommendations are the weakest signifier of recommendation, and can non be used to disregard recommendations developed from higher degrees of grounds. [ 1-3 ] This recommendation conveys the care of good unwritten hygiene and seemingly, it is the lone consensus recommendation in the new guideline. Oral hygiene steps are available and inexpensive, supply possible benefit, are consistent with current clinical pattern and are in harmony with good unwritten wellness. [ 3 ]Goals and Implications for Clinical PracticeThe rate of OI infection is recorded from 0.3 % to 8.3 % in the available published literature. Invasion of beings into the surgical lesion during the surgery, haematogenous spread, return of infection in antecedently involved and septic articulations, or extension from an morbific local beginning may bring forth such infection. [ 1 ] Established on the best bing grounds, the rational for this clinical pattern guideline is to help the related clinicians and tooth doctors to take a paramount preventing and intervention mode when it is needed. Contemporary dental pattern necessarily depends on evidence-based criterions and stipulates doctors and tooth doctors to use the best available grounds for intervention planning in their clinical pattern. That ‘s why this guideline consists a systematic reappraisal of literature, conducted between October 2010 and July 2011 by AAOS and ADA methodologists and the doctor/dentist vocational groups and declared wherever the grounds was equal or unequal.They even discussed the spreads in the literature, where future researches are peculiarly needed. [ 1 ] Jevsevar, an orthopedic sawbones and president of the AAOS squad, declared that this clinical pattern guideline was non supposed to be an impartial papers and he confirmed that clinicians should utilize it as an informative tool in their intervention planning to better the quality and efficaciousness of their wellness attention. [ 3 ] In drumhead, the guideline is deliberated to carry on clinical pattern and besides to supply a beginning of information for all qualified practicians covering with bar of OI infection in dental patients. The AAOS and ADA hope that this guideline would besides help to guarantee patients sing the logics behind their intervention planning. [ 1 ] Therefore, The new guideline replaces the old AAOS Information Statement and the full guideline with all wining certificates and workgroup declarations is available to entree on the AAOS web site: hypertext transfer protocol: //www.aaos.org/research/guidelines/PUDP/PUDP_guideline.pdf and the ADA web site: hypertext transfer protocol: //www.ada.org/sections/professionalResources/pdfs/PUDP_guideline.pdf

Saturday, November 9, 2019

Acadamic Misconduct Essay

Academic misconduct is described as academic integrity violation for the unfair advantage of oneself or unfair academic advantage or disadvantage to others in academic community, academic misconduct can be a plagiarism, cheating, and collusion but not limited. The other academic misconduct activities such as not obeying academic staff directions regarding assessments and group work submissions, falsifying reports, having/spreading examination materials without unit teacher permission, arranging someone to do assessment work all these included as academic misconduct. If an allegation arises towards a student and if it’s proven in an investigation then student has to face penalties under student academic misconduct policy. In this essay we going to discuss in brief about plagiarism, cheating, collusion and academic misconduct procedural process depending on minor or substantial misconduct when allegations arise and appeal for the student. As per UWS policy Plagiarism is defined as an â€Å"act of presenting material as one’s own without appropriate acknowledgement that constitutes plagiarism, not the intension of the student when doing so†, for example when student submits work in which words or ideas are presented as their own as intentional or unintentional without proper acknowledgment of the original author such as website, other students work, lecture, journal article or book. Cheating is described as any attempt to give or obtain assistance in a formal academic exercise such as examination, without due acknowledgment such as speaking to other students during examination, carrying any information materials such as textbooks, using electronics devices such as mobile, Bluetooth any other items which are prohibited by examination supervisor. Collusion is where two or more people engage in plagiarism, cheating or encourage others to do so. According to UWS Academic misconduct policy there are Minor misconduct and substantial misconduct. A Minor misconduct is determine by the university as a minimal threat to integrity of the student assessment in writing such as lack of referencing or academic requirements. A substantial misconduct is determine by the university as a major threat to integrity such as, when a student repeats minor misconduct activities intentionally, any allegations in the examination and any allegations related to collusion. In the process of investigating the allegations unit teacher, unit coordinator, Dean, school academic committee and student academic committee will be involved. in the first stage of Investigation process and hearing of academic misconduct, If unit teacher or examination supervisor believe that there is any academic misconduct happened, and they have evidence or reasons to support, teacher of the unit will report to unit coordinator with relevant documentation by signed copy or email, then with in five working days unit coordinator will send copy of allegation to the Dean. The dean, will advise unit coordinator to do investigation, and then unit coordinator and unit teacher decides to do further investigation, unit teacher will notify the student and invite for meeting in writing by post and email. Student can attend meeting with fellow student or university academic staff member or a student welfare officer. Meeting will be organised between 8 – 15 working days after on invitation letter despatch date. Student must respond to the invitation with in seven working days date of despatch whether he / she will attend the meeting or not. The decision will be made on the allegation even in the student absence. If unit coordinator decides that the allegation is not substantial he / she will dismiss it. Other penalties like refer to academic counselling, student require to re-submit assessment task after re-submission unit coordinator makes a decision on the marks and grades student may get zero marks. If the unit coordinator determine its substantial he/ she will be referred to relevant dean for decision. After going through all the process as discussed earlier in which case the unit coordinator will send the invitation letter to student for meeting with dean. After meeting if dean decides it’s not substantial dean will dismiss the allegation. When dean decides the allegations substantial then dean can penalise student such as recommend to counselling, ask for re-submission of work, if required student has to sit for exam again, dean will decide marks and grades. If dean judges that the allegation very substantial or too serious then dean refers that allegation to SAC (student academic committee). After going all the process as discussed above, student will have meeting with SAC members. After meeting if SAC decides if allegation are true it will take any action of dean penalties or combination of them, or suspend the student from university minimum period of 6months not more than 12 months, or dismiss the student for minimum of 12 months not more than 24 months in this case student has to apply for readmission or SAC can suspend the student permanently from the university. A student can appeal against the unit coordinators decision when student considers that the decision was made against the procedural fairness or when student not agreeing with allegations or when student considers that there is a substantial new evidence which was not available previously to unit coordinator or when student considers the penalty imposed by unit coordinator was too severe. Student must appeal within 15 days with evidence in writing to dean from the date of the letter advising of unit coordinators decision. It is the responsibility of every student to respect and obey the policy of UWS for academic misconduct to maintain academic integrity among academic community, when allegations were proven the student has to face severe penalties imposed by university academic committee besides the appeal options for student, The best option for students is to work hard on their own and get help when needed from academic teachers before submitting any academic work.

Thursday, November 7, 2019

Vimy Ridge essays

Vimy Ridge essays In the past 100 years 25 major events in history have helped shape Canada into the fine country it is now. The battle of Vimy Ridge stands out among them. People from non-Canadian countries went to this battle as French, British, and others came back from the war Canadian heroes. Vimy Ridge is just one of 25 major events in the past 100 years. On August, 1914 the recruitment began with a monumental force of 650, 000 men. All the men had reasons for joining some honorable others not like evading the law or fleeing their wives. This Canadian Expeditionary Force and Canada Corps has been the greatest achievement by Canada since confederation. Then the key event occurred on Easter Monday, 1917 Canadian Corps launched a perfectly planned assault on the Germans. The Germans were positioned on the top of Vimy Ridge had fortified the line so effectively that it held back 4 earlier attempts to take the ridge. This time the Canadians had proper training and artillery to make this fifth and final attempt their finest work ever. The battle techniques were developed by a McGill University and engineering professor and lieutenant colonel Andy McNaughton. They mapped out and destroyed German gun positions in the days before the assault. The early morning attack had 19, 200 men in eight brigades The Germans front line was either killed or unhinged by the first wave of attacks. That left an impregnable area for the Canadians to effectively take over the position. Sadly, 10, 602 Canadians died protecting our freedom. These people were brave and unrelenting for our freedom; these are our true Canadian heroes. The battle of Vimy Ridge is argued to be the event that led to Canada being a successful nation. After November 11, 1918 Canada was viewed as a more serious manner than ever before. Although Vimy Ridge never led to any allied breakthrough this was still a very important event in history. ...

Monday, November 4, 2019

Schedule and Cost Control Techniques Essay Example | Topics and Well Written Essays - 750 words

Schedule and Cost Control Techniques - Essay Example (Mochal, 2007)The benefit for this technique is the fact that it takes into account three different scenarios in order to complete the whole picture thus ensuring that project doesn't bring surprises. The basic fact behind the success of PERT is the fact that it intends to capture wider areas of estimates so that managers can have all the possible indications of how the project may behave given these conditions happen and based on their judgment and experience they choose the best estimate. Further, what is most beneficial in the use of PERT is the fact that it takes into the uncertainty related with the project. By taking into account the three difference scenarios, it tends to capture the uncertainty therefore there are very minimal chances of something going awry until and unless project encounters something which is entirely external and out of the control of the project managers. Thus PERT not only not assist and scheduling and estimating of the project but helps in making tradeoffs between project and segments. Similarly, EVM or earned value management is another tool available to project managers which can greatly help to view projects in more objective way. Essentially, EVM tends to measure technical performance, schedule performance and cost performance using one single estimation methodology. However, what is most important with this methodology is the fact that it can provide early warning signals if applied properly thus it provides a very accurate method of ensuring that if followed properly, it can help avoid the big surprises during the project life cycle. Further to this, what is more critical and valuable about this approach is the fact that it helps achieve the measurement of cost performance therefore ensuring that projects besides remaining within the technical parameters also remain within the budgets so that risk tradeoffs could be made between the whole project and the segments. This is important in the sense that It provides a better grip over the affairs of the project besides ensuring that the costs remain within the control and all the associated risks with the project are balanced with proper risk and return tradeoff. However one more important thing that EVM fail to capture is the quality of the project otherwise it tend to focus clearly on ensuring that the schedules as well as ensuring that the risk tradeoffs between the various segments of the project and project itself are well managed. Risk Metric is another tool which can greatly help to normalize the project as it can greatly help achieve to minimize the risks associated with the projects. (Ferguson, 2004) it provides the required visibility into the uncertainities related with the project thus it is most valuable in assessing and making risk return trade off in the projects besides ensuring that the costs and other estimates and schedules are properly prepared and are within the limits. "The proposed metric can be applied early and throughout the project. It has been useful for identifying or canceling projects in trouble. It has also been useful for identifying projects that do not yet have a satisfactory risk plan." (Ferguson, 2004). Further Risk Metric can also allow project managers to check the compliance of the project with the standards and procedures set in the beginning of the project. Conclusion There are various tools and techniques available to ensure that during the

Saturday, November 2, 2019

Meaning of Life Essay Example | Topics and Well Written Essays - 1000 words

Meaning of Life - Essay Example Besides these tortures, he encountered constant threats of being thrown into the gas ovens probably because of his physical appearance. However, in spite of the experiences he faced in the three camps that he served, he emerged as a visionary person. His reason for being optimistic was that human beings hold the freedom of choosing the manner in which they view the circumstances they undergo on a daily basis. Therefore, they create meaning from such circumstances. Frankl outlined three experiences that the prisoners went through after their arrival at the concentration camps, during their stay there and after they were freed from the camps. After realizing where they had been taken to and the reason for their transfer, the first experience that the prisoners felt was the shock. Later, the shock would be replaced by a second experience. The experience would be the phase of psychological reaction as well as apathy. These were the necessary methods that the prisoners would use to cope with the abuse that they received from their supervisors. During this stage, the fear of death was no longer the prisoners’ concern. On the contrary, the part that was most painful was the insults that they received. The prisoners would be given uniforms that were more of rags (Frankl, 7-26). Also, they would be issued with shoes most of which did not fit them. Those who had reported with better shoes had no choice but to give them to the SS guards or risk s evere punishments. At a time, the prisoners were forced to walk bare footed on the snow since their shoes had been worn out. The author describes a twelve-year-old boy who he saw being taken to the sickbay. The boy had been forced to stand attention on the snow bear footed for hours because there were no shoes for him at the camp. The results were that the boy’s toes got some frostbites. Frankl writes that there was a frequent